Opportunity Information: Apply for RFA HL 20 003
The Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk (DECIPHeR) opportunity (RFA HL 20 003) is a National Institutes of Health (NIH), Department of Health and Human Services cooperative agreement funding announcement designed to reduce and ultimately eliminate cardiovascular and/or pulmonary health disparities in communities carrying a high burden of heart and lung disease risk. The central goal is not to invent new clinical treatments, but to take interventions that are already proven effective and figure out the best, most practical ways to get them adopted, delivered well, and sustained over time in real-world community, public health, and routine clinical settings so they produce the largest possible population health impact.
This announcement specifically emphasizes T4 implementation research. In this context, T4 work focuses on identifying, testing, and refining strategies that increase the consistent uptake and long-term maintenance of evidence-based interventions in everyday practice. In other words, applicants are expected to study how to make known solutions actually reach people who need them, especially in places where disparities persist because of barriers like limited access to care, under-resourced public health infrastructure, structural inequities, or challenges in coordinating services across organizations. Projects should be community-level in nature and aimed at improving population outcomes, with an explicit focus on disparity reduction.
The funding mechanism is a cooperative agreement (UG3/UH3) with clinical trial optional, meaning applicants may propose studies that do or do not meet NIH’s definition of a clinical trial. The UG3/UH3 structure generally supports a phased approach, where an initial stage supports planning, refinement, and readiness activities, and a later stage supports full implementation and testing once milestones are met. Because it is a cooperative agreement rather than a traditional grant, awardees should expect substantial programmatic involvement from NIH staff, typically including collaborative oversight, milestone-driven transitions between phases, and coordination intended to maximize rigor, reproducibility, and real-world relevance.
Eligible applicants are broad and include many organizations positioned to carry out community-engaged implementation research. Eligibility spans state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (outside of higher education institutions); for-profit organizations other than small businesses; and small businesses, plus additional eligible entities as described in the full announcement. This wide eligibility signals that NIH is looking for cross-sector capacity, including partnerships that can integrate clinical systems, public health agencies, and community-based organizations.
Financially, the announcement lists an award ceiling of $635,000 and anticipates approximately 8 awards. The associated CFDA numbers are 93.837, 93.838, and 93.840, reflecting alignment with NIH heart, lung, blood, and sleep-related research programs. The opportunity was created March 11, 2019, with an original closing date of October 1, 2019.
At a practical level, strong applications under DECIPHeR would be expected to do more than demonstrate that an intervention works. They would focus on the implementation strategy itself: how delivery will be coordinated across real community settings, what barriers to adoption and sustainability are being addressed, how effectiveness and reach will be measured in high-burden communities, and how the work will contribute to measurable reductions in cardiovascular and/or pulmonary disparities. The emphasis on coordinated, community-level delivery suggests projects will often involve multi-partner collaborations and approaches designed for scale and durability, not just short-term program success.Apply for RFA HL 20 003
- The Department of Health and Human Services, National Institutes of Health in the health sector is offering a public funding opportunity titled "Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk (DECIPHeR) (UG3/UH3 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837, 93.838, 93.840.
- This funding opportunity was created on Mar 11, 2019.
- Applicants must submit their applications by Oct 01, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $635,000.00 in funding.
- The number of recipients for this funding is limited to 8 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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| Funding Opportunity |
|---|
| Disparities Elimination through Coordinated Interventions to Prevent and Control Heart and Lung Disease Risk (DECIPHeR) - Research Coordinating Center (RCC) (U24 Clinical Trial Not Allowed) Apply for RFA HL 20 004 Funding Number: RFA HL 20 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $485,000 |
| Limited Competition: Dental, Oral and Craniofacial Tissue Regeneration Consortium (U24 Clinical Trial Not Allowed) Apply for RFA DE 19 010 Funding Number: RFA DE 19 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $4,000,000 |
| BLOODSAFE: Research to enhance availability of safe blood for patients with severe anemia and hemorrhagic conditions in low or lower-middle income countries (LLMICs) in Sub-Saharan Africa - Data Coordinating Center (DCC) (U24 Clinical Trial Not Allow Apply for RFA HL 20 010 Funding Number: RFA HL 20 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $850,000 |
| BLOODSAFE: Research to enhance availability of safe blood for patients with severe anemia and hemorrhagic conditions in low or lower-middle income countries (LLMICs) in Sub-Saharan Africa (UG3/UH3 Clinical Trial Optional) Apply for RFA HL 20 009 Funding Number: RFA HL 20 009 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $415,000 |
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| Traumatic Brain Injury State Partnership Program Partner State Funding Opportunity Apply for HHS 2019 ACL AOD TBSG 0348 Funding Number: HHS 2019 ACL AOD TBSG 0348 Agency: Department of Health and Human Services, Administration for Community Living Category: Health Funding Amount: $150,000 |
| Limited Competition Centers of Excellence in Ethical, Legal and Social Implications (ELSI) Research (CEER) (RM1 Clinical Trial Optional) Apply for RFA HG 19 012 Funding Number: RFA HG 19 012 Agency: Department of Health and Human Services, National Institutes of Health Category: Health Funding Amount: $650,000 |
| Key Population Community HIV Services Action and Response (KP-CARE 1) Activity Apply for 72062019RFA00003 Funding Number: 72062019RFA00003 Agency: Agency for International Development, Nigeria USAID-Abuja Category: Health Funding Amount: Case Dependent |
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