Opportunity Information: Apply for HRSA 22 077

The MCH Adolescent and Young Adult Health Research Network (AYAH-RN) grant (HRSA 22-077) is a Health Resources and Services Administration (HRSA) discretionary funding opportunity from the U.S. Department of Health and Human Services. It is structured as a cooperative agreement, meaning the federal agency expects to have substantial involvement in how the work is carried out, not just provide funds and step back. The program focuses on adolescents and young adults (AYA), defined here as ages 10 through 25, and it is designed to strengthen a national, multi-site research network that can move evidence into real-world Maternal and Child Health (MCH) practice faster and more consistently.

At its core, the opportunity is about building and maintaining the kind of shared infrastructure that makes a research network function well across multiple sites. That includes leadership and coordination capacity, common methods and processes, collaboration supports, and a clear strategy for translating research findings into practice. HRSA highlights that the network should be positioned to respond to both emerging and persistent public health challenges affecting AYA populations, with special attention to the reality that underserved and disadvantaged youth and young adults often experience poorer outcomes and face greater barriers to care.

The announcement lays out several major aims for the AYAH-RN. One of the central goals is to grow and extend a national, collaborative research network that accelerates translation of research into MCH AYA practice. In practical terms, that points to work that does not stop at producing studies, but also emphasizes dissemination, implementation, and uptake in clinical, community, and systems settings. Another priority is improving access to, use of, and quality of preventive health care for adolescents and young adults, including well-visits. The program also stresses integrating mental, emotional, and behavioral health into primary care and/or school-based settings, reflecting a whole-person approach that treats behavioral health as a standard part of AYA care rather than an add-on.

HRSA also calls for the network to address major trends shaping AYA health and the delivery of services. Examples specifically mentioned include alignment with a changing health care system, technological advances, shifts in substance use patterns, and demographic trends such as changes in racial and ethnic composition across AYA populations. The long-term impacts of COVID-19 are singled out as a continuing concern, including vaccine hesitancy and the pandemic’s effects on mental, emotional, and behavioral health. The intent is for the network to generate and translate actionable knowledge that helps systems adapt to these evolving conditions, rather than focusing only on static or narrowly defined issues.

Equity is an explicit throughline. The opportunity emphasizes developing innovative, empirically sound strategies to increase equity in health and safety outcomes for AYA, with a focus on underserved populations. That signals interest in approaches that are evidence-based, measurable, and grounded in real implementation settings, including strategies that reduce disparities in access, quality, experiences of care, and outcomes. It also implies that the network’s work should account for social and structural factors that shape health, not only individual-level behaviors.

Another major component is workforce and capacity-building for the field. Applicants are expected to coordinate a plan to enhance research training and mentorship for diverse emerging MCH investigators. The notice points to using innovative mentorship and research experiences and supporting manuscript development, indicating that the network should function as a pipeline and professional development platform, not just a research production unit. In addition, the program aims to improve health outcomes during the transition from adolescence to young adulthood, a period when many young people face disruptions in coverage, changes in providers, and shifting developmental and social demands.

Finally, the network is expected to accelerate dissemination and translation into practice of new and emerging research findings related to AYA health, including insights from developmental neuroscience and other relevant fields. HRSA specifically mentions areas like the science of puberty, prevention, and mental, emotional, and behavioral health. This reflects an expectation that the network will draw on multidisciplinary science and help practitioners and systems apply newer research to real decisions, policies, and service models.

In terms of basic grant mechanics, the opportunity listed an award ceiling of $450,000 and anticipated making one award. Eligible applicants include Federally recognized tribal governments, other tribal organizations, and nonprofit organizations with 501(c)(3) status (excluding institutions of higher education), along with other entities as clarified in the full eligibility language. The opportunity was posted December 15, 2021, with an original closing date of March 15, 2022.

  • The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "MCH Adolescent and Young Adult Health Research Network (AYAH-RN)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.110.
  • This funding opportunity was created on Dec 15, 2021.
  • Applicants must submit their applications by Mar 15, 2022 I. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $450,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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