Opportunity Information: Apply for RFA DA 27 007
The NIH is soliciting applications under a limited competition funding opportunity (RFA-DA-27-007) to create and run a research education course that helps researchers in the drug use, drug misuse, and drug addiction space turn scientific discoveries into real-world solutions. The central idea is to build practical capacity in product development, entrepreneurship, and innovation pathways so that investigators can move biomedical concepts beyond early-stage research and toward implementation or commercialization. Rather than funding a typical research project, this award is meant to support an organized, skills-focused training program that blends structured instruction with mentorship and hands-on activities, with the intent of accelerating the development of products that can address the complex challenges associated with substance use and addiction.
The course envisioned by this NOFO is designed to meet a specific gap: many addiction-focused scientists have strong technical expertise, but limited exposure to the steps required to translate a discovery into something that can be deployed in clinics, communities, or markets. The program is therefore expected to emphasize the practical realities of innovation, including how to shape an idea into a feasible product concept, evaluate user and stakeholder needs, plan development milestones, and navigate the business and regulatory considerations that commonly determine whether a promising scientific insight ever becomes usable. A key feature is the combination of training, mentorship, and experiential learning, which together should help participants practice the translation process rather than only learning it in theory. Another explicit aim is community-building, fostering an interdisciplinary network of investigators who can collaborate across science, clinical considerations, implementation, regulatory strategy, and commercialization.
This opportunity is offered as a cooperative agreement (funding instrument type UE5), meaning the NIH expects substantial involvement with the awardee during planning and execution compared with a standard grant. The NOFO also states "Clinical Trial Not Allowed," so the supported activities should not include clinical trials as defined by NIH. The activity category is Health, and the CFDA number associated with this program is 93.279. Only one award is expected, reinforcing that the intent is to establish a single course/program with broad impact rather than multiple separate efforts.
Eligibility is broad across U.S.-based organizational types, including state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits (both 501(c)(3) and non-501(c)(3), excluding institutions of higher education in those nonprofit categories as specified); for-profit organizations other than small businesses; small businesses; and other eligible entities described in the NOFO. However, the NOFO is explicit that foreign organizations are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined in the NIH Grants Policy Statement) are not allowed. In practical terms, applicants must plan for a fully domestic program structure and execution.
Key administrative details include an original application closing date of 2026-10-01 and a creation date of 2026-06-23. The listing does not specify an award ceiling in the provided source data. Applicants are directed to consult Section III (Eligibility Information) in the full NOFO for any additional constraints that may apply under this limited competition structure.Apply for RFA DA 27 007
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Growing Great Ideas: Research Education Course in Entrepreneurship and Product Development for Researchers Studying Drug Use, Drug Misuse, and Drug Addiction (UE5 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
- This funding opportunity was created on 2026-06-23.
- Applicants must submit their applications by 2026-10-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NIH Limited Competition RFA-DA-27-007 (UE5) Research Education Course
What is this NIH funding opportunity about?
This limited competition NIH opportunity (RFA-DA-27-007) seeks an organization to create and run a research education course that helps investigators working in drug use, drug misuse, and drug addiction translate scientific discoveries into real-world solutions.
What is the main goal of the funded program?
The goal is to build practical capacity in product development, entrepreneurship, and innovation pathways so researchers can move biomedical concepts beyond early-stage research and toward implementation or commercialization.
Is this funding meant to support a typical research project?
No. The award is intended to support an organized, skills-focused training program (a research education course) rather than a traditional research project.
What kinds of activities is the course expected to include?
The course is expected to blend structured instruction with mentorship and hands-on, experiential learning activities so participants can practice translation and innovation processes rather than only learning them in theory.
What gap is this program intended to address?
The program is designed to address the gap that many addiction-focused scientists have strong technical expertise but limited exposure to the steps required to translate a discovery into something deployable in clinics, communities, or markets.
What practical topics should the program emphasize?
Based on the description, the program should emphasize practical realities of innovation such as shaping an idea into a feasible product concept, evaluating user and stakeholder needs, planning development milestones, and navigating business and regulatory considerations that affect whether discoveries become usable.
What does NIH mean by moving discoveries toward implementation or commercialization?
In this context, it means supporting investigators in learning how to progress biomedical concepts from early-stage research toward real-world use, including pathways that may lead to implementation in practice settings or commercialization.
Why does the opportunity mention product development and entrepreneurship?
The course is intended to equip researchers with innovation skills often needed to translate science into deployable solutions, including product development thinking and entrepreneurship-oriented pathways.
Is mentorship an explicit requirement or expectation?
Yes. A key feature described in the opportunity is the combination of training, mentorship, and experiential learning.
Is community-building part of the program’s purpose?
Yes. An explicit aim is community-building to foster an interdisciplinary network of investigators who can collaborate across scientific, clinical, implementation, regulatory strategy, and commercialization perspectives.
What funding instrument will NIH use for this award?
This opportunity uses a cooperative agreement funding instrument (UE5).
What does it mean that this is a cooperative agreement (UE5)?
A cooperative agreement means NIH expects substantial involvement with the awardee during planning and execution compared with a standard grant.
Are clinical trials allowed under this opportunity?
No. The NOFO specifies “Clinical Trial Not Allowed,” meaning supported activities should not include clinical trials as defined by NIH.
How many awards does NIH expect to make?
Only one award is expected, indicating NIH intends to establish a single course/program with broad impact rather than fund multiple separate efforts.
What is the activity category for this opportunity?
The activity category is Health.
What CFDA number is associated with this program?
The CFDA number associated with this program is 93.279.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizational types, including state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits (both 501(c)(3) and non-501(c)(3), excluding institutions of higher education in those nonprofit categories as specified); for-profit organizations other than small businesses; small businesses; and other eligible entities described in the NOFO.
Are foreign organizations eligible to apply?
No. The NOFO explicitly states that foreign organizations are not eligible to apply.
Can a U.S. organization apply if it plans to run parts of the program outside the United States?
No. The NOFO states that non-U.S. components of U.S. organizations are not eligible and that foreign components (as defined in the NIH Grants Policy Statement) are not allowed, implying the program must be fully domestic in structure and execution.
What is the application due date?
The original application closing date listed is 2026-10-01.
What is the creation date of this listing?
The listing creation date is 2026-06-23.
Is an award ceiling specified in the provided information?
No. The provided source data does not specify an award ceiling.
Where should applicants look for additional eligibility constraints?
Applicants are directed to consult Section III (Eligibility Information) in the full NOFO for any additional constraints, especially because this is a limited competition opportunity.
What does “limited competition” imply based on the information provided?
The description identifies this as a limited competition funding opportunity and advises reviewing the NOFO’s eligibility section for additional constraints, indicating there may be specific limitations beyond the broad organizational categories listed.
What is the expected impact of funding a single program?
Because only one award is expected, the intent described is to establish one course/program with broad impact that can build translation and innovation capacity across the addiction research community.
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